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Evidence against a role of P-glycoprotein in the clearance of the Alzheimer’s disease Aβ(1–42) peptides

It has been proposed that the amyloid-β peptides (Aβ) cause the neuronal degeneration in the Alzheimer’s disease brain. An imbalance between peptide production at the neuronal level and their elimination across the blood–brain–barrier (BBB) results in peptide accumulation inside the brain. The ident...

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Bibliografski detalji
Izdano u:Cell Stress Chaperones
Glavni autori: Bello, Ivan, Salerno, Milena
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406933/
https://ncbi.nlm.nih.gov/pubmed/25591827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-014-0566-8
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