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Evidence for impaired amyloid β clearance in Alzheimer's disease

Alzheimer's disease (AD) is a common neurodegenerative disease characterized by the accumulation of extracellular plaques and intracellular tangles. Recent studies support the hypothesis that the accumulation of amyloid beta (Aβ) peptide within the brain arises from an imbalance of the producti...

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Autori principali: Wildsmith, Kristin R, Holley, Monica, Savage, Julie C, Skerrett, Rebecca, Landreth, Gary E
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978761/
https://ncbi.nlm.nih.gov/pubmed/23849219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt187
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