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Evidence for impaired amyloid β clearance in Alzheimer's disease

Alzheimer's disease (AD) is a common neurodegenerative disease characterized by the accumulation of extracellular plaques and intracellular tangles. Recent studies support the hypothesis that the accumulation of amyloid beta (Aβ) peptide within the brain arises from an imbalance of the producti...

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Detalhes bibliográficos
Main Authors: Wildsmith, Kristin R, Holley, Monica, Savage, Julie C, Skerrett, Rebecca, Landreth, Gary E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978761/
https://ncbi.nlm.nih.gov/pubmed/23849219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt187
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