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Structural insight into MtmC, a bifunctional ketoreductase-methyltransferase involved in the assembly of the mithramycin trisaccharide chain

More and more post-PKS tailoring enzymes are recognized to be multifunctional and co-dependent on other tailoring enzymes. One of the recently discovered intriguing examples is MtmC, a bifunctional TDP-4-keto-d-olivose ketoreductase-methyltransferase, which – in co-dependence with glycosyltransferas...

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Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Chen, Jhong Min, Hou, Caxia, Wang, Guojun, Tsodikov, Oleg V., Rohr, Jürgen
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406830/
https://ncbi.nlm.nih.gov/pubmed/25587924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501462g
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