טוען...
How mithramycin stereochemistry dictates its structure and DNA binding function
An aureolic acid natural product mithramycin (MTM) has been known for its potent antineoplastic properties. MTM inhibits cell growth by binding in the minor groove of double-stranded DNA as a dimer, in which the two molecules of MTM are coordinated to each other through a divalent metal ion. A cryst...
שמור ב:
| הוצא לאור ב: | Medchemcomm |
|---|---|
| Main Authors: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Royal Society of Chemistry
2019
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6533888/ https://ncbi.nlm.nih.gov/pubmed/31191864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00100j |
| תגים: |
הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|