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Gentamicin differentially alters cellular metabolism of cochlear hair cells as revealed by NAD(P)H fluorescence lifetime imaging

Aminoglycoside antibiotics are implicated as culprits of hearing loss in more than 120,000 individuals annually. Research has shown that the sensory cells, but not supporting cells, of the cochlea are readily damaged and/or lost after use of such antibiotics. High-frequency outer hair cells (OHCs) s...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Biomed Opt
Κύριοι συγγραφείς: Zholudeva, Lyandysha V., Ward, Kristina G., Nichols, Michael G., Smith, Heather Jensen
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Society of Photo-Optical Instrumentation Engineers 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405084/
https://ncbi.nlm.nih.gov/pubmed/25688541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.20.5.051032
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