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Aminoglycosides rapidly inhibit NAD(P)H metabolism increasing reactive oxygen species and cochlear cell demise
Despite causing permanent hearing loss by damaging inner ear sensory cells, aminoglycosides (AGs) remain one of the most widely used classes of antibiotics in the world. Although the mechanisms of cochlear sensory cell damage are not fully known, reactive oxygen species (ROS) are clearly implicated....
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| Publicado no: | J Biomed Opt |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society of Photo-Optical Instrumentation Engineers
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6225535/ https://ncbi.nlm.nih.gov/pubmed/30411553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.24.5.051403 |
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