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Natural history of β-cell adaptation and failure in type 2 diabetes

Type 2 diabetes mellitus (T2D) is a complex disease characterized by β-cell failure in the setting of insulin resistance. The current evidence suggests that genetic predisposition, and environmental factors can impair the capacity of the β-cells to respond to insulin resistance and ultimately lead t...

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Bibliographic Details
Published in:Mol Aspects Med
Main Authors: Alejandro, Emilyn U., Gregg, Brigid, Blandino-Rosano, Manuel, Cras-Méneur, Corentin, Bernal-Mizrachi, Ernesto
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404183/
https://ncbi.nlm.nih.gov/pubmed/25542976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mam.2014.12.002
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