Advanced age is associated with worsened outcomes and a unique genomic response in severely injured patients with hemorrhagic shock

INTRODUCTION: We wished to characterize the relationship of advanced age to clinical outcomes and to transcriptomic responses after severe blunt traumatic injury with hemorrhagic shock. METHODS: We performed epidemiological, cytokine, and transcriptomic analyses on a prospective, multi-center cohort...

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Publicat a:Crit Care
Autors principals: Vanzant, Erin L, Hilton, Rachael E, Lopez, Cecilia M, Zhang, Jianyi, Ungaro, Ricardo F, Gentile, Lori F, Szpila, Benjamin E, Maier, Ronald V, Cuschieri, Joseph, Bihorac, Azra, Leeuwenburgh, Christiaan, Moore, Frederick A, Baker, Henry V, Moldawer, Lyle L, Brakenridge, Scott C, Efron, Philip A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404112/
https://ncbi.nlm.nih.gov/pubmed/25880307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-015-0788-x
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