A BETTER UNDERSTANDING OF WHY MURINE MODELS OF TRAUMA DO NOT RECAPITULATE THE HUMAN SYNDROME

OBJECTIVE: Genomic analyses from blood leukocytes have concluded that mouse injury poorly reflects human trauma at the leukocyte transcriptome. Concerns have focused on the modest severity of murine injury models, differences in murine compared to human age, dissimilar circulating leukocyte populati...

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Detaylı Bibliyografya
Yayımlandı:Crit Care Med
Asıl Yazarlar: Gentile, Lori F., Nacionales, Dina C., Lopez, M. Cecilia, Vanzant, Erin, Cuenca, Angela, Cuenca, Alex G., Ungaro, Ricardo, Baslanti, Tezcan Ozrazgat, McKinley, Bruce A., Bihorac, Azra, Cuschieri, Joseph, Maier, Ronald V., Moore, Frederick A., Leeuwenburgh, Christiaan, Baker, Henry V., Moldawer, Lyle L., Efron, Philip A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283139/
https://ncbi.nlm.nih.gov/pubmed/24413577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000000222
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