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Ebola Virus VP35 Interaction with Dynein LC8 Regulates Viral RNA Synthesis
Ebola virus VP35 inhibits alpha/beta interferon production and functions as a viral polymerase cofactor. Previously, the 8-kDa cytoplasmic dynein light chain (LC8) was demonstrated to interact with VP35, but the functional consequences were unclear. Here we demonstrate that the interaction is direct...
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| Publicado en: | J Virol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4403485/ https://ncbi.nlm.nih.gov/pubmed/25741013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03652-14 |
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