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DRBP76 Associates With Ebola Virus VP35 and Suppresses Viral Polymerase Function
The Zaire Ebola virus (EBOV) protein VP35 is multifunctional; it inhibits IFN-α/β production and functions as a cofactor of the viral RNA polymerase. Mass spectrometry identified the double stranded RNA binding protein 76 (DRBP76/NFAR-1/NF90) as a cellular factor that associates with the VP35 C-term...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3218669/ https://ncbi.nlm.nih.gov/pubmed/21987769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir343 |
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