The crystal structure of DR6 in complex with the amyloid precursor protein provides insight into death receptor activation

The amyloid precursor protein (APP) has garnered considerable attention due to its genetic links to Alzheimer's disease. Death receptor 6 (DR6) was recently shown to bind APP via the protein extracellular regions, stimulate axonal pruning, and inhibit synapse formation. Here, we report the crys...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Genes Dev
Asıl Yazarlar: Xu, Kai, Olsen, Olav, Tzvetkova-Robev, Dorothea, Tessier-Lavigne, Marc, Nikolov, Dimitar B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2015
Konular:
Research Communication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403255/
https://ncbi.nlm.nih.gov/pubmed/25838500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.257675.114
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller