Regulatory T cells require TCR signaling for their suppressive function

Regulatory T cells (Tregs) are a subset of CD4(+) T cells that maintain immune tolerance in part by their ability to inhibit the proliferation of conventional CD4(+) T cells (Tconvs). The role of the T cell receptor (TCR) and the downstream signaling pathways required for this suppressive function o...

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Publicat a:J Immunol
Autors principals: Schmidt, Amanda M., Lu, Wen, Sindhava, Vishal J., Huang, Yanping, Burkhardt, Janis K., Yang, Enjun, Riese, Matthew J., Maltzman, Jonathan S., Jordan, Martha S., Kambayashi, Taku
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402269/
https://ncbi.nlm.nih.gov/pubmed/25821220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402384
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