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ERBB3 Independent Activation of the PI3K Pathway in EGFR Mutant Lung Adenocarcinomas

ERBB3, a member of the Epidermal Growth Factor Receptor (EGFR) family of receptor tyrosine kinases, has been implicated in activation of the phosphatidyl-inositol 3-kinase (PI3K) pathway in human lung adenocarcinomas driven by EGFR mutations. We investigated the contribution of ERBB3 to the initiati...

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Publicat a:Cancer Res
Autors principals: Song, Xiaoling, Fan, Pang-Dian, Bantikassegn, Amlak, Guha, Udayan, Threadgill, David W., Varmus, Harold, Politi, Katerina
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400867/
https://ncbi.nlm.nih.gov/pubmed/25596284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1625
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