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ERBB3 Independent Activation of the PI3K Pathway in EGFR Mutant Lung Adenocarcinomas
ERBB3, a member of the Epidermal Growth Factor Receptor (EGFR) family of receptor tyrosine kinases, has been implicated in activation of the phosphatidyl-inositol 3-kinase (PI3K) pathway in human lung adenocarcinomas driven by EGFR mutations. We investigated the contribution of ERBB3 to the initiati...
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| Udgivet i: | Cancer Res |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4400867/ https://ncbi.nlm.nih.gov/pubmed/25596284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1625 |
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