DOK2 Inhibits EGFR-Mutated Lung Adenocarcinoma

Somatic mutations in the EGFR proto-oncogene occur in ~15% of human lung adenocarcinomas and the importance of EGFR mutations for the initiation and maintenance of lung cancer is well established from mouse models and cancer therapy trials in human lung cancer patients. Recently, we identified DOK2...

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Autori principali: Berger, Alice H., Chen, Ming, Morotti, Alessandro, Janas, Justyna A., Niki, Masaru, Bronson, Roderick T., Taylor, Barry S., Ladanyi, Marc, Van Aelst, Linda, Politi, Katerina, Varmus, Harold E., Pandolfi, Pier Paolo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821857/
https://ncbi.nlm.nih.gov/pubmed/24255704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079526
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