DOK2 Inhibits EGFR-Mutated Lung Adenocarcinoma

Somatic mutations in the EGFR proto-oncogene occur in ~15% of human lung adenocarcinomas and the importance of EGFR mutations for the initiation and maintenance of lung cancer is well established from mouse models and cancer therapy trials in human lung cancer patients. Recently, we identified DOK2...

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Hlavní autoři: Berger, Alice H., Chen, Ming, Morotti, Alessandro, Janas, Justyna A., Niki, Masaru, Bronson, Roderick T., Taylor, Barry S., Ladanyi, Marc, Van Aelst, Linda, Politi, Katerina, Varmus, Harold E., Pandolfi, Pier Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821857/
https://ncbi.nlm.nih.gov/pubmed/24255704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079526
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