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Immune checkpoint blockade: a common denominator approach to cancer therapy

The immune system recognizes and is poised to eliminate cancer, but is held in check by inhibitory receptors and ligands. These immune checkpoint pathways, which normally maintain self-tolerance and limit collateral tissue damage during anti-microbial immune responses, can be co-opted by cancer to e...

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Podrobná bibliografie
Vydáno v:Cancer Cell
Hlavní autoři: Topalian, Suzanne L., Drake, Charles G., Pardoll, Drew M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400238/
https://ncbi.nlm.nih.gov/pubmed/25858804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.03.001
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