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Neoadjuvant checkpoint blockade for cancer immunotherapy

Cancer immunotherapies that target the programmed cell death 1 (PD-1):programmed death-ligand1 (PD-L1) immune checkpoint pathway have ushered in the modern oncology era. Drugs that block PD-1 or PD-L1 facilitate endogenous antitumor immunity and, because of their broad activity spectrum, have been r...

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Bibliografiske detaljer
Udgivet i:Science
Main Authors: Topalian, Suzanne L., Taube, Janis M., Pardoll, Drew M.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789854/
https://ncbi.nlm.nih.gov/pubmed/32001626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aax0182
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