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Immune checkpoint blockade: a common denominator approach to cancer therapy

The immune system recognizes and is poised to eliminate cancer, but is held in check by inhibitory receptors and ligands. These immune checkpoint pathways, which normally maintain self-tolerance and limit collateral tissue damage during anti-microbial immune responses, can be co-opted by cancer to e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Cell
Prif Awduron: Topalian, Suzanne L., Drake, Charles G., Pardoll, Drew M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400238/
https://ncbi.nlm.nih.gov/pubmed/25858804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.03.001
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