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Immune checkpoint blockade: a common denominator approach to cancer therapy
The immune system recognizes and is poised to eliminate cancer, but is held in check by inhibitory receptors and ligands. These immune checkpoint pathways, which normally maintain self-tolerance and limit collateral tissue damage during anti-microbial immune responses, can be co-opted by cancer to e...
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| Udgivet i: | Cancer Cell |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4400238/ https://ncbi.nlm.nih.gov/pubmed/25858804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.03.001 |
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