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Combination Approaches with Immune-Checkpoint Blockade in Cancer Therapy

In healthy individuals, immune-checkpoint molecules prevent autoimmune responses and limit immune cell-mediated tissue damage. Tumors frequently exploit these molecules to evade eradication by the immune system. Over the past years, immune-checkpoint blockade of cytotoxic T lymphocyte antigen-4 and...

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: Swart, Maarten, Verbrugge, Inge, Beltman, Joost B.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088186/
https://ncbi.nlm.nih.gov/pubmed/27847783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2016.00233
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