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Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy

With recent approvals for multiple therapeutic antibodies that block cytotoxic T lymphocyte associated antigen 4 (CTLA4) and programmed cell death protein 1 (PD1) in melanoma, non-small-cell lung cancer and kidney cancer, and additional immune checkpoints being targeted clinically, many questions st...

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Dades bibliogràfiques
Publicat a:Nat Rev Cancer
Autors principals: Topalian, Suzanne L., Taube, Janis M., Anders, Robert A., Pardoll, Drew M.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5381938/
https://ncbi.nlm.nih.gov/pubmed/27079802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc.2016.36
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