Predictive biomarkers for immune checkpoint blockade and opportunities for combination therapies

Immune checkpoint blockade therapies (ICBs) are a prominent breakthrough in cancer immunotherapy in recent years (named the 2013 “Breakthrough of the Year” by the Science magazine). Thus far, FDA-approved ICBs primarily target immune checkpoints CTLA-4, PD-1, and PD-L1. Notwithstanding their impress...

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Bibliografiske detaljer
Udgivet i:Genes Dis
Main Authors: Shen, Hongxing, Yang, Eddy Shih-Hsin, Conry, Marty, Fiveash, John, Contreras, Carlo, Bonner, James A., Shi, Lewis Zhichang
Format: Artigo
Sprog:Inglês
Udgivet: Chongqing Medical University 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997608/
https://ncbi.nlm.nih.gov/pubmed/32042863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2019.06.006
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