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Hepatitis C Virus Structural Proteins can Exacerbate or Ameliorate Acetaminophen-induced Liver Injury in Mice
Chronic Hepatitis C virus (HCV) infection pre-disposes patients to develop liver failure after acetaminophen (APAP) overdose. Mechanisms involved in this were explored using transgenic mice expressing the HCV structural proteins core, E1 and E2. Treatment of C57BL/6J mice with 200 mg/kg body weight...
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| Publicado en: | Arch Toxicol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4398656/ https://ncbi.nlm.nih.gov/pubmed/25743375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-015-1498-5 |
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