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Complete dissociation of the HIV-1 gp41 ectodomain and membrane proximal regions upon phospholipid binding
The envelope glycoprotein gp41 mediates the process of membrane fusion that enables entry of the HIV-1 virus into the host cell. Strong lipid affinity of the ectodomain suggests that its heptad repeat regions play an active role in destabilizing membranes by directly binding to the lipid bilayers an...
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| Опубликовано в: : | J Biomol NMR |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4398632/ https://ncbi.nlm.nih.gov/pubmed/25631354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-015-9900-4 |
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