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Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase

Lysosomal phospholipase A2 (LPLA2) and lecithin:cholesterol acyltransferase (LCAT) belong to a structurally uncharacterized family of key lipid metabolizing enzymes responsible for lung surfactant catabolism and for reverse cholesterol transport, respectively. Whereas LPLA2 is predicted to underlie...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Glukhova, Alisa, Hinkovska-Galcheva, Vania, Kelly, Robert, Abe, Akira, Shayman, James A, Tesmer, John JG
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397983/
https://ncbi.nlm.nih.gov/pubmed/25727495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7250
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