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The Effects of Tissue-Nonspecific Alkaline Phosphatase Gene Therapy on Craniosynostosis and Craniofacial Morphology in the FGFR2(C342Y/+) Mouse Model of Crouzon Craniosynostosis
OBJECTIVES: Craniosynostosis, the premature fusion of cranial bones, has traditionally been described as a disease of increased bone mineralization. However, multiple mouse models of craniosynostosis display craniosynostosis simultaneously with diminished cranial bone volume and/or density. We propo...
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| Publicado no: | Orthod Craniofac Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4396711/ https://ncbi.nlm.nih.gov/pubmed/25865549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ocr.12080 |
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