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Viral delivery of tissue nonspecific alkaline phosphatase diminishes craniosynostosis in one of two FGFR2(C342Y/+) mouse models of Crouzon syndrome
Craniosynostosis is the premature fusion of cranial bones. The goal of this study was to determine if delivery of recombinant tissue nonspecific alkaline phosphatase (TNAP) could prevent or diminish the severity of craniosynostosis in a C57BL/6 FGFR2(C342Y/+) model of neonatal onset craniosynostosis...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7259715/ https://ncbi.nlm.nih.gov/pubmed/32470062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234073 |
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