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Endothelial-Derived Oxidative Stress Drives Myofibroblastic Activation and Calcification of the Aortic Valve

AIMS: Oxidative stress is present in and contributes to calcification of the aortic valve, but the driving factors behind the initiation of valve oxidative stress are not well understood. We tested whether the valve endothelium acts as an initiator and propagator of oxidative stress in aortic valve...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Farrar, Emily J., Huntley, Geoffrey D., Butcher, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395382/
https://ncbi.nlm.nih.gov/pubmed/25874717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123257
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