Crystallinity of Hydroxyapatite Drives Myofibroblastic Activation and Calcification in Aortic Valves

Calcific aortic valve disease (CAVD) is an inexorably degenerative pathology characterized by progressive calcific lesion formation on the valve leaflets. The interaction of valvular cells in advanced lesion environments is not well understood yet highly relevant as clinically detectable CAVD exhibi...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: Richards, Jennifer M., Kunitake, Jennie A. M. R., Hunt, Heather B., Wnorowski, Alexa N., Lin, Debra W., Boskey, Adele L., Donnelly, Eve, Estroff, Lara A., Butcher, Jonathan T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899951/
https://ncbi.nlm.nih.gov/pubmed/29505892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2018.02.024
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