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Heterogeneous susceptibility of valve endothelial cells to mesenchymal transformation in response to TNFα

Lack of understanding of the early mechanisms of aortic valve stenosis and calcification hinders the development of diagnostic and therapeutic intervention strategies. Inflammation is a known component of early aortic valve disease (AVD) and can induce mesenchymal transformation in a subset of aorti...

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Detalhes bibliográficos
Main Authors: Farrar, Emily J., Butcher, Jonathan T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905205/
https://ncbi.nlm.nih.gov/pubmed/23982279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-013-0894-3
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