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Effects of shear stress pattern and magnitude on mesenchymal transformation and invasion of aortic valve endothelial cells

Understanding the role of mechanical forces on cell behavior is critical for tissue engineering, regenerative medicine, and disease initiation studies. Current hemodynamic bioreactors are largely limited to 2D substrates or the application of general flow conditions at a tissue level, which eliminat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biotechnol Bioeng
Hauptverfasser: Mahler, Gretchen J., Frendl, Christopher M., Cao, Qingfeng, Butcher, Jonathan T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472486/
https://ncbi.nlm.nih.gov/pubmed/24898772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25291
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