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Inflammatory cytokines promote mesenchymal transformation in embryonic and adult valve endothelial cells

OBJECTIVE: Inflammatory activation of valve endothelium is an early phase of aortic valve disease pathogenesis, but subsequent mechanisms are poorly understood. Adult valve endothelial cells retain the developmental ability to undergo endothelial to mesenchymal transformation (EndMT), but a biologic...

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Bibliografski detalji
Glavni autori: Mahler, Gretchen J., Farrar, Emily J., Butcher, Jonathan T.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694265/
https://ncbi.nlm.nih.gov/pubmed/23104848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300504
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