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Inflammatory cytokines promote mesenchymal transformation in embryonic and adult valve endothelial cells
OBJECTIVE: Inflammatory activation of valve endothelium is an early phase of aortic valve disease pathogenesis, but subsequent mechanisms are poorly understood. Adult valve endothelial cells retain the developmental ability to undergo endothelial to mesenchymal transformation (EndMT), but a biologic...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3694265/ https://ncbi.nlm.nih.gov/pubmed/23104848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300504 |
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