Synthesis of a Sugar-Based Thiosemicarbazone Series and Structure-Activity Relationship versus the Parasite Cysteine Proteases Rhodesain, Cruzain, and Schistosoma mansoni Cathepsin B1

The pressing need for better drugs against Chagas disease, African sleeping sickness, and schistosomiasis motivates the search for inhibitors of cruzain, rhodesain, and Schistosoma mansoni CB1 (SmCB1), the major cysteine proteases from Trypanosoma cruzi, Trypanosoma brucei, and S. mansoni, respectiv...

詳細記述

保存先:
書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Fonseca, Nayara Cristina, da Cruz, Luana Faria, da Silva Villela, Filipe, do Nascimento Pereira, Glaécia Aparecida, de Siqueira-Neto, Jair Lage, Kellar, Danielle, Suzuki, Brian M., Ray, Debalina, de Souza, Thiago Belarmino, Alves, Ricardo José, Júnior, Policarpo Ademar Sales, Romanha, Alvaro José, Murta, Silvane Maria Fonseca, McKerrow, James H., Caffrey, Conor R., de Oliveira, Renata Barbosa, Ferreira, Rafaela Salgado
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
Chemistry; Biosynthesis
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394791/
https://ncbi.nlm.nih.gov/pubmed/25712353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04601-14
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料