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Efficacy of the Investigational Echinocandin ASP9726 in a Guinea Pig Model of Invasive Pulmonary Aspergillosis

ASP9726 is an investigational echinocandin with in vitro activity against Aspergillus species. We evaluated the pharmacokinetics and efficacy of this agent in an established guinea pig model of invasive pulmonary aspergillosis. ASP9726 plasma concentrations were measured in guinea pigs administered...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Wiederhold, Nathan P., Najvar, Laura K., Matsumoto, Satoru, Bocanegra, Rosie A., Herrera, Monica L., Wickes, Brian L., Kirkpatrick, William R., Patterson, Thomas F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394786/
https://ncbi.nlm.nih.gov/pubmed/25753643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04857-14
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