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Efficacy of the Investigational Echinocandin ASP9726 in a Guinea Pig Model of Invasive Pulmonary Aspergillosis

ASP9726 is an investigational echinocandin with in vitro activity against Aspergillus species. We evaluated the pharmacokinetics and efficacy of this agent in an established guinea pig model of invasive pulmonary aspergillosis. ASP9726 plasma concentrations were measured in guinea pigs administered...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Wiederhold, Nathan P., Najvar, Laura K., Matsumoto, Satoru, Bocanegra, Rosie A., Herrera, Monica L., Wickes, Brian L., Kirkpatrick, William R., Patterson, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394786/
https://ncbi.nlm.nih.gov/pubmed/25753643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04857-14
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