Efficacy of the Investigational Echinocandin ASP9726 in a Guinea Pig Model of Invasive Pulmonary Aspergillosis

ASP9726 is an investigational echinocandin with in vitro activity against Aspergillus species. We evaluated the pharmacokinetics and efficacy of this agent in an established guinea pig model of invasive pulmonary aspergillosis. ASP9726 plasma concentrations were measured in guinea pigs administered...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Wiederhold, Nathan P., Najvar, Laura K., Matsumoto, Satoru, Bocanegra, Rosie A., Herrera, Monica L., Wickes, Brian L., Kirkpatrick, William R., Patterson, Thomas F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2015
Gaiak:
Experimental Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394786/
https://ncbi.nlm.nih.gov/pubmed/25753643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04857-14
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