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Efficacy of the Investigational Echinocandin ASP9726 in a Guinea Pig Model of Invasive Pulmonary Aspergillosis

ASP9726 is an investigational echinocandin with in vitro activity against Aspergillus species. We evaluated the pharmacokinetics and efficacy of this agent in an established guinea pig model of invasive pulmonary aspergillosis. ASP9726 plasma concentrations were measured in guinea pigs administered...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Wiederhold, Nathan P., Najvar, Laura K., Matsumoto, Satoru, Bocanegra, Rosie A., Herrera, Monica L., Wickes, Brian L., Kirkpatrick, William R., Patterson, Thomas F.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394786/
https://ncbi.nlm.nih.gov/pubmed/25753643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04857-14
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