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Sequential or Combination Antifungal Therapy with Voriconazole and Liposomal Amphotericin B in a Guinea Pig Model of Invasive Aspergillosis

We evaluated combinations of voriconazole (VRC) and liposomal amphotericin B (L-AMB) in a guinea pig invasive aspergillosis model. Simultaneous VRC and L-AMB was most effective, although VRC monotherapy was also effective. These regimens as well as sequential L-AMB followed by VRC were more effectiv...

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Detalhes bibliográficos
Main Authors: Kirkpatrick, William R., Coco, Brent J., Patterson, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426916/
https://ncbi.nlm.nih.gov/pubmed/16569887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1567-1569.2006
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