Efficacy of Combination Antifungal Therapy with Intraperitoneally Administered Micafungin and Aerosolized Liposomal Amphotericin B against Murine Invasive Pulmonary Aspergillosis

Targeted intrapulmonary delivery of drugs may reduce systemic toxicity and improve treatment efficacy. In the current study, we evaluated the effects of a combination treatment consisting of inhalation of aerosolized liposomal amphotericin B (L-AMB) with intraperitoneal administration of micafungin...

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Main Authors: Takazono, Takahiro, Izumikawa, Koichi, Mihara, Tomo, Kosai, Kosuke, Saijo, Tomomi, Imamura, Yoshifumi, Miyazaki, Taiga, Seki, Masafumi, Kakeya, Hiroshi, Yamamoto, Yoshihiro, Yanagihara, Katsunori, Kohno, Shigeru
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715619/
https://ncbi.nlm.nih.gov/pubmed/19528281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00285-09
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