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An adenosine triphosphate-independent proteasome activator contributes to the virulence of Mycobacterium tuberculosis

Mycobacterium tuberculosis encodes a proteasome that is highly similar to eukaryotic proteasomes and is required to cause lethal infections in animals. The only pathway known to target proteins for proteasomal degradation in bacteria is pupylation, which is functionally analogous to eukaryotic ubiqu...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Jastrab, Jordan B., Wang, Tong, Murphy, J. Patrick, Bai, Lin, Hu, Kuan, Merkx, Remco, Huang, Jessica, Chatterjee, Champak, Ovaa, Huib, Gygi, Steven P., Li, Huilin, Darwin, K. Heran
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394314/
https://ncbi.nlm.nih.gov/pubmed/25831519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423319112
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