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Structural analysis of the dodecameric proteasome activator PafE in Mycobacterium tuberculosis
The human pathogen Mycobacterium tuberculosis (Mtb) requires a proteasome system to cause lethal infections in mice. We recently found that proteasome accessory factor E (PafE, Rv3780) activates proteolysis by the Mtb proteasome independently of adenosine triphosphate (ATP). Moreover, PafE contribut...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4833279/ https://ncbi.nlm.nih.gov/pubmed/27001842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1512094113 |
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