An adenosine triphosphate-independent proteasome activator contributes to the virulence of Mycobacterium tuberculosis

Mycobacterium tuberculosis encodes a proteasome that is highly similar to eukaryotic proteasomes and is required to cause lethal infections in animals. The only pathway known to target proteins for proteasomal degradation in bacteria is pupylation, which is functionally analogous to eukaryotic ubiqu...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Jastrab, Jordan B., Wang, Tong, Murphy, J. Patrick, Bai, Lin, Hu, Kuan, Merkx, Remco, Huang, Jessica, Chatterjee, Champak, Ovaa, Huib, Gygi, Steven P., Li, Huilin, Darwin, K. Heran
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394314/
https://ncbi.nlm.nih.gov/pubmed/25831519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423319112
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