An adenosine triphosphate-independent proteasome activator contributes to the virulence of Mycobacterium tuberculosis

Mycobacterium tuberculosis encodes a proteasome that is highly similar to eukaryotic proteasomes and is required to cause lethal infections in animals. The only pathway known to target proteins for proteasomal degradation in bacteria is pupylation, which is functionally analogous to eukaryotic ubiqu...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Jastrab, Jordan B., Wang, Tong, Murphy, J. Patrick, Bai, Lin, Hu, Kuan, Merkx, Remco, Huang, Jessica, Chatterjee, Champak, Ovaa, Huib, Gygi, Steven P., Li, Huilin, Darwin, K. Heran
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
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PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394314/
https://ncbi.nlm.nih.gov/pubmed/25831519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423319112
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