The Mycobacterium tuberculosis Pup-proteasome system regulates nitrate metabolism through an essential protein quality control pathway

The human pathogen Mycobacterium tuberculosis encodes a proteasome that carries out regulated degradation of bacterial proteins. It has been proposed that the proteasome contributes to nitrogen metabolism in M. tuberculosis, although this hypothesis had not been tested. Upon assessing M. tuberculosi...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Becker, Samuel H., Jastrab, Jordan B., Dhabaria, Avantika, Chaton, Catherine T., Rush, Jeffrey S., Korotkov, Konstantin V., Ueberheide, Beatrix, Darwin, K. Heran
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386731/
https://ncbi.nlm.nih.gov/pubmed/30723150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1819468116
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