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Proteasome substrate capture and gate opening by the accessory factor PafE from Mycobacterium tuberculosis

In all domains of life, proteasomes are gated, chambered proteases that require opening by activators to facilitate protein degradation. Twelve proteasome accessory factor E (PafE) monomers assemble into a single dodecameric ring that promotes proteolysis required for the full virulence of the human...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Hu, Kuan, Jastrab, Jordan B., Zhang, Susan, Kovach, Amanda, Zhao, Gongpu, Darwin, K. Heran, Li, Huilin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880150/
https://ncbi.nlm.nih.gov/pubmed/29414791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001471
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