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Proteasome substrate capture and gate opening by the accessory factor PafE from Mycobacterium tuberculosis
In all domains of life, proteasomes are gated, chambered proteases that require opening by activators to facilitate protein degradation. Twelve proteasome accessory factor E (PafE) monomers assemble into a single dodecameric ring that promotes proteolysis required for the full virulence of the human...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5880150/ https://ncbi.nlm.nih.gov/pubmed/29414791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001471 |
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