Hypoxic induction of AKAP12 variant 2 shifts PKA-mediated protein phosphorylation to enhance migration and metastasis of melanoma cells

Scaffold proteins are critical hubs within cells that have the ability to modulate upstream signaling molecules and their downstream effectors to fine-tune biological responses. Although they can serve as focal points for association of signaling molecules and downstream pathways that regulate tumor...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Finger, Elizabeth C., Castellini, Laura, Rankin, Erinn B., Vilalta, Marta, Krieg, Adam J., Jiang, Dadi, Banh, Alice, Zundel, Wayne, Powell, Marianne Broome, Giaccia, Amato J.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2015
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394282/
https://ncbi.nlm.nih.gov/pubmed/25792458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1418164112
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