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Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress

The initiation of apoptosis often transpires in the presence of agents that regulate cell survival. This study evaluated the effects of stress-induced ceramide on the anti-apoptotic activity of the phosphoinositide-3 kinase [PI(3)K] pathway. PI(3)K activity is directly down-regulated by stress-induc...

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Detalhes bibliográficos
Main Authors: Zundel, Wayne, Giaccia, Amato
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316964/
https://ncbi.nlm.nih.gov/pubmed/9649498
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