Regional imbalanced activation of the calcineurin/BAD apoptotic pathway and the PI3K/Akt survival pathway after myocardial infarction

BACKGROUND: The underlying molecular mechanisms of the remodeling after myocardial infarction (MI) remain unclear. The purpose of this study was to investigate the role of a survival pathway (PI3K/Akt) and an apoptosis pathway (calcineurin/BAD) in the remodeling after MI in a large animal model. MET...

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Détails bibliographiques
Auteurs principaux: Li, Tieluo, Kilic, Ahmet, Wei, Xufeng, Wu, Changfu, Schwartzbauer, Gary, Yankey, G. Kwame, DeFilippi, Christopher, Bond, Meredith, Wu, Zhongjun J, Griffith, Bartley P
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303985/
https://ncbi.nlm.nih.gov/pubmed/22088220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2011.10.107
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