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Structure of smAKAP and its regulation by PKA-mediated phosphorylation

The A-kinase anchoring protein (AKAP) smAKAP has three extraordinary features; it is very small, it is anchored directly to membranes by acyl motifs, and it interacts almost exclusively with the type I regulatory subunits (RI) of cAMP-dependent kinase (PKA). Here, we determined the crystal structure...

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Detalhes bibliográficos
Publicado no:FEBS J
Main Authors: Burgers, Pepijn P., Bruystens, Jessica, Burnley, Rebecca J., Nikolaev, Viacheslav O., Keshwani, Malik, Wu, Jian, Janssen, Bert J. C., Taylor, Susan S., Heck, Albert J. R., Scholten, Arjen
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980077/
https://ncbi.nlm.nih.gov/pubmed/27028580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13726
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