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Influence of domain interactions on conformational mobility of the progesterone receptor detected by hydrogen/deuterium exchange mass spectrometry

Structural and functional details of the N-terminal activation function 1 (AF1) of most nuclear receptors are poorly understood due to the highly dynamic intrinsically disordered nature of this domain. A hydrogen/deuterium exchange (HDX) mass spectrometry based investigation of TATA box binding prot...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Goswami, Devrishi, Callaway, Celetta, Pascal, Bruce D., Kumar, Raj, Edwards, Dean P., Griffin, Patrick R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393884/
https://ncbi.nlm.nih.gov/pubmed/24909783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.04.013
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