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SMARTS: reconstructing disease response networks from multiple individuals using time series gene expression data

Motivation: Current methods for reconstructing dynamic regulatory networks are focused on modeling a single response network using model organisms or cell lines. Unlike these models or cell lines, humans differ in their background expression profiles due to age, genetics and life factors. In additio...

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Détails bibliographiques
Publié dans:Bioinformatics
Auteurs principaux: Wise, Aaron, Bar-Joseph, Ziv
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393515/
https://ncbi.nlm.nih.gov/pubmed/25480376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu800
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